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The peptide & supplement tracking library

63 structured, source-backed entries — 24 peptides plus medications, and 24 supplements — covering research status, how each compound works, what people commonly track, and the questions worth bringing to a clinician. Free to read. Education only, not medical advice.

Reta is a tracking and education tool — not a medical provider. Nothing here is a diagnosis, treatment, prescription, or dosing recommendation. Peptides and medications should only be used under the direction of a licensed clinician. Talk to a qualified clinician before starting, stopping, combining, or changing anything. Many compounds below are not FDA-approved for human use; some are investigational or sold through unregulated channels where purity and dosing are not guaranteed.

63 entries

Retatrutide

medication
InvestigationalInvestigational metabolic (GLP-1 / GIP / glucagon triple agonist)

Retatrutide is an experimental once-weekly injectable being studied for obesity and type 2 diabetes. It is the first triple agonist (acting on GLP-1, GIP, and glucagon receptors) to reach Phase 3. Because it is investigational, it is only legitimately available through clinical trials — products sold elsewhere are unregulated and of unknown identity, purity, and dose.

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Tirzepatide

medication
FDA-approvedMetabolic medication (GIP / GLP-1 receptor agonist)

Tirzepatide is a prescription once-weekly injectable that activates two incretin receptors (GIP and GLP-1). It is approved and clinician-managed. People using it commonly track appetite, food tolerance, protein intake, and weight, because appetite and gastric emptying are strongly affected.

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Semaglutide

medication
FDA-approvedMetabolic medication (GLP-1 receptor agonist)

Semaglutide is a prescription GLP-1 receptor agonist, injectable weekly (Ozempic/Wegovy) or oral daily (Rybelsus). It is approved and clinician-managed. Appetite reduction is prominent, so protein intake and hydration are commonly tracked.

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CJC-1295

peptide
Not FDA-approvedGrowth-hormone secretagogue (GHRH analog)

CJC-1295 is a synthetic analog of growth-hormone-releasing hormone (GHRH) discussed in recovery, sleep, and body-composition contexts, frequently paired with ipamorelin. It is not an approved medication; human evidence is limited.

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Ipamorelin

peptide
Not FDA-approvedGrowth-hormone secretagogue (ghrelin/GHRP receptor agonist)

Ipamorelin is a selective growth-hormone secretagogue often discussed alongside CJC-1295. It is not approved; human data are limited.

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Tesamorelin

peptide
FDA-approved (specific use)Growth-hormone-releasing hormone analog

Tesamorelin (Egrifta) is the only FDA-approved GHRH analog, approved specifically for HIV-associated lipodystrophy. It is sometimes discussed more broadly for visceral fat; that broader use is off-label and a clinician-level decision.

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Sermorelin

peptide
Formerly approved / compoundedGrowth-hormone-releasing hormone analog

Sermorelin is a GHRH analog historically used to assess growth-hormone deficiency and now common in wellness/longevity clinics via compounding. It is usually framed as a gentler secretagogue; it is still clinician-territory.

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AOD-9604

peptide
Not FDA-approvedGrowth-hormone fragment

AOD-9604 is a fragment of the growth-hormone molecule marketed in fat-loss contexts. It is not approved, and clinical fat-loss evidence in humans is weak. Worth a frank clinician conversation about whether it adds anything over fundamentals.

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MOTS-c

peptide
Not FDA-approvedMitochondrial-derived peptide (investigational)

MOTS-c is a mitochondrial-derived peptide studied in metabolism and exercise-physiology research. Human clinical evidence is early; it is not an approved medication.

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BPC-157

peptide
Not FDA-approvedRecovery-focused research peptide

BPC-157 is a synthetic peptide widely discussed for soft-tissue and gut recovery. It has not been approved for human use and lacks completed human clinical trials. Anyone considering it should discuss legality, sourcing, and safety directly with a clinician.

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TB-500

peptide
Not FDA-approvedRecovery-focused research peptide

TB-500 is a peptide fragment discussed in injury-recovery communities, often alongside BPC-157. It is not approved for human use and human data are sparse. Clinician guidance is essential.

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GLOW Stack

other
Not FDA-approvedStacks & Combinations

The GLOW Stack commonly refers to a vendor or community combination of GHK-Cu, BPC-157, and TB-500. It is discussed around skin appearance, soft-tissue recovery, and general repair signaling, but it is not a validated or standardized treatment plan.

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KLOW Stack

other
Not FDA-approvedStacks & Combinations

KLOW Stack commonly refers informally to GHK-Cu, BPC-157, TB-500, and KPV. Vendor and community formulations can differ, no fixed ratio is authoritative, and evidence for the combined formulation is limited.

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Wolverine Stack

other
Not FDA-approvedStacks & Combinations

The Wolverine Stack commonly refers to the pairing of BPC-157 and TB-500 in injury-recovery communities. The name is popular, but neither compound is FDA-approved for human use and human evidence remains limited.

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Retatrutide + Tesamorelin

other
InvestigationalStacks & Combinations

This combination is discussed at the intersection of GLP/GIP/glucagon research and growth-hormone-axis therapy. It should be understood as an educational overview, not a protocol or recommendation.

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Retatrutide + Tesamorelin + Ipamorelin

other
InvestigationalStacks & Combinations

This triple combination is discussed in body-composition communities, combining a metabolic investigational drug with GH-axis agents. The combination has no standardized clinical role in Reta's current data.

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CJC-1295 + Ipamorelin

other
Not FDA-approvedStacks & Combinations

CJC-1295 plus ipamorelin is a widely discussed secretagogue pairing intended to stimulate the body's own growth-hormone pulses. Human evidence for wellness use is limited, and the combination requires clinician-level risk review.

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Common GLP-1 and Growth-Hormone-Pathway Combinations

other
InvestigationalStacks & Combinations

People commonly discuss pairing GLP-1 or multi-incretin medications with GH-pathway agents for body composition, appetite, recovery, or visceral-fat goals. Reta presents this as an educational map, not a recommended protocol.

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Myostatin Inhibitors Overview

other
InvestigationalStacks & Combinations

Myostatin inhibitors aim to reduce signaling that limits muscle growth. The category includes clinical-stage medicines for muscle-wasting disorders, older discontinued programs, animal research tools, and community-discussed research peptides.

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GHK-Cu

peptide
Cosmetic (topical)Skin / repair peptide (topical cosmetic; injectable unapproved)

GHK-Cu is a copper-binding peptide. In topical skincare it is mainstream and regulated as a cosmetic. Injectable use is a different, unapproved risk category and needs clinician oversight.

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Melanotan II

peptide
Not FDA-approvedMelanocortin agonist (tanning; unapproved, higher-risk)

Melanotan II is an unapproved melanocortin-receptor agonist marketed for tanning and libido effects. It is unregulated, and there are documented safety concerns, including reports of new or changing moles/melanoma during or after use.

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NAD+

other
Dietary supplementCoenzyme / longevity wellness

NAD+ is a coenzyme central to cellular energy metabolism. Oral precursors (NMN, NR) are supplements; IV/injectable NAD+ is a clinic-based wellness offering, not an approved therapy. Benefits in humans are still being studied.

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Glutathione

other
Dietary supplementAntioxidant (oral/IV wellness)

Glutathione is the body's major intracellular antioxidant. Oral supplements exist; IV glutathione is marketed for skin and 'detox' but is not FDA-approved for those uses, and safety of unregulated IV products is a concern.

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L-carnitine (injectable)

other
FDA-approved (specific use)Amino-acid derivative (supplement; injectable Rx for deficiency)

L-carnitine helps transport fatty acids into mitochondria for energy. Oral supplements are common; prescription injectable levocarnitine is approved only for carnitine deficiency. Fat-loss/performance injections are off-label with limited evidence.

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PT-141 (Bremelanotide)

medication
FDA-approved (specific use)Melanocortin agonist (sexual health)

Bremelanotide is a melanocortin-receptor agonist approved for a specific sexual-desire condition in premenopausal women and discussed more broadly for libido. Broader use is off-label and a clinician-level decision; unregulated products carry identity and purity risks.

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Thymosin Alpha-1

peptide
Not FDA-approvedImmune-modulating peptide

Thymosin Alpha-1 is a naturally occurring peptide discussed in immune-modulation contexts. It is not FDA-approved in the US; human evidence for wellness use is limited, and any use should be clinician-directed.

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Thymosin Beta-4

peptide
Not FDA-approvedRecovery-focused research peptide

Thymosin Beta-4 is a naturally occurring peptide discussed in tissue-repair contexts and closely related to the marketed TB-500 fragment. It is not approved for human use and human data are sparse — clinician guidance is essential.

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SS-31 (Elamipretide)

peptide
InvestigationalMitochondrial-targeted peptide

SS-31 (elamipretide) is an investigational mitochondria-targeting peptide studied in specific disease trials. It is not an approved medication, and general wellness evidence is not established.

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Epitalon

peptide
Not FDA-approvedLongevity research peptide

Epitalon is a synthetic peptide discussed in longevity and sleep/circadian contexts. It is not approved for human use, and robust human evidence is lacking — a frank clinician conversation is warranted.

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DSIP

peptide
Not FDA-approvedSleep research peptide

DSIP is a naturally occurring peptide discussed in sleep and stress-response contexts. It is not approved for human use, and human data are limited — track sleep honestly and involve a clinician.

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KPV

peptide
Not FDA-approvedAnti-inflammatory research peptide

KPV is a short peptide discussed in inflammation and gut-comfort contexts. It is not approved for human use, and human evidence is limited — clinician guidance is essential.

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LL-37

peptide
Not FDA-approvedAntimicrobial research peptide

LL-37 is a naturally occurring antimicrobial peptide studied in immune and wound-context research. It is not approved for human use, and supplemental-use evidence is limited — clinician guidance is essential.

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Selank

peptide
Not FDA-approvedAnxiolytic / nootropic research peptide

Selank is a synthetic peptide discussed in anxiety and cognition contexts. It is not FDA-approved, and human evidence outside a small research base is limited — clinician guidance is essential.

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Semax

peptide
Not FDA-approvedNootropic research peptide

Semax is a synthetic peptide discussed in cognition and focus contexts, commonly used intranasally. It is not FDA-approved, and human evidence outside a limited research base is small — clinician guidance is essential.

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IGF-1 LR3

peptide
Not FDA-approvedInsulin-like growth factor analog

IGF-1 LR3 is a modified insulin-like growth factor discussed in muscle-growth contexts. It is not approved for human use and carries real safety concerns — this entry exists to inform, not to guide use.

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Hexarelin

peptide
Not FDA-approvedGrowth-hormone secretagogue

Hexarelin is a growth-hormone secretagogue discussed alongside other GH peptides. It is not approved for human use; human data are limited and GH-axis effects warrant clinician oversight.

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GHRP-2

peptide
Not FDA-approvedGrowth-hormone secretagogue

GHRP-2 is a growth-hormone-releasing peptide discussed for recovery and body composition, often alongside a GHRH analog. It is not approved for human use; human data are limited.

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GHRP-6

peptide
Not FDA-approvedGrowth-hormone secretagogue

GHRP-6 is a growth-hormone-releasing peptide known for a strong hunger effect, discussed for recovery and body composition. It is not approved for human use; human data are limited.

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Kisspeptin

peptide
InvestigationalReproductive-hormone research peptide

Kisspeptin is a naturally occurring peptide central to reproductive-hormone signaling and studied in fertility research. It is not an approved medication; wellness-use evidence is not established.

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Creatine monohydrate

supplement
Dietary supplementPerformance / muscle

Creatine monohydrate is among the most-studied supplements, commonly used to support strength, training output, and muscle over time. Inexpensive and well tolerated by most people; consistency matters more than timing.

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Magnesium

supplement
Dietary supplementSleep / recovery

A mineral many people under-consume. Glycinate is commonly chosen for evening use and sleep; citrate leans laxative. Often tracked alongside a wind-down routine.

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Omega-3 (fish/krill oil)

supplement
Dietary supplementGeneral health

EPA/DHA fatty acids commonly taken for cardiovascular and general health, and discussed for joint comfort and recovery. Quality varies between products.

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Vitamin D

supplement
Dietary supplementGeneral health

Commonly supplemented, especially with limited sun exposure. One of the few supplements where a cheap blood test tells you exactly where you stand — worth testing rather than guessing.

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Vitamin C

supplement
Dietary supplementVitamins

A water-soluble vitamin commonly supplemented for general and immune health. Most people can meet needs from food; supplements are commonly tracked during winter or heavy training blocks.

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Vitamin B12

supplement
Dietary supplementVitamins

B12 supports red blood cells and nerve function. Deficiency is most common with plant-based diets, older age, or acid-reducing medications — a blood test tells you where you stand.

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B-complex

supplement
Dietary supplementVitamins

A combination of B vitamins (B1, B2, B3, B5, B6, B7, B9, B12) involved in energy metabolism. Commonly tracked as a morning habit; bright-yellow urine afterward is normal (riboflavin).

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Vitamin K2

supplement
Dietary supplementVitamins

A fat-soluble vitamin discussed for bone and cardiovascular health, and commonly paired with vitamin D3. Anyone on blood thinners needs a clinician conversation before touching vitamin K in any form.

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Zinc

supplement
Dietary supplementMinerals / electrolytes

An essential mineral involved in immune function, skin, and hormone metabolism. Commonly tracked seasonally or during heavy training. Long-term high doses deplete copper — dose matters.

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Potassium

supplement
Dietary supplementMinerals / electrolytes

An electrolyte most people under-consume relative to sodium. Food (fruit, vegetables, dairy) is the primary source; supplements are capped at small doses because too much potassium is genuinely dangerous, especially with kidney issues or certain medications.

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Electrolyte blend

supplement
Dietary supplementHydration / electrolytes

Drink mixes combining sodium, potassium, and often magnesium. Commonly tracked alongside water targets — especially with heavy sweating, low-carb eating, or reduced appetite on GLP-class medications where fluid intake drops.

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Protein powder

supplement
Dietary supplementPerformance / muscle

A convenient way to close the gap to a daily protein target — especially useful when appetite is suppressed and whole-food volume is hard. Whey, casein, and plant blends all work; total daily protein matters most.

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Collagen peptides

supplement
Dietary supplementPerformance / joints & skin

Hydrolyzed collagen commonly tracked for joint comfort, skin, and connective-tissue support, often taken with vitamin C. Evidence is moderate for joint comfort and skin hydration; it is not a complete protein for muscle purposes.

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EAAs / BCAAs

supplement
Dietary supplementPerformance / muscle

Free-form amino acids marketed around training. If daily protein is already adequate, they add little — most useful for training fasted or when whole protein isn't practical. EAAs (all nine essentials) are generally preferred over BCAAs alone.

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Pre-workout

supplement
Dietary supplementPerformance

Multi-ingredient formulas usually built around caffeine, often with citrulline and beta-alanine. Effects and stimulant content vary enormously between products; the caffeine dose is the number to actually track.

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Melatonin

supplement
Dietary supplementSleep / recovery

A hormone your body already makes to signal darkness. Most useful for shifting sleep timing (jet lag, schedule changes); lower doses are commonly discussed as sufficient. It's a timing signal, not a sedative.

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Glycine

supplement
Dietary supplementSleep / recovery

A simple amino acid discussed for sleep quality, often taken before bed. Small studies suggest improved subjective sleep; it's inexpensive, mildly sweet, and well tolerated.

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L-theanine

supplement
Dietary supplementSleep / calm focus

An amino acid from tea discussed for calm focus without sedation. Commonly paired with caffeine during the day (smoothing jitters) or taken in the evening as part of a wind-down.

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Ashwagandha

supplement
Dietary supplementRecovery / stress

An adaptogenic herb discussed for stress, sleep, and recovery. Trials suggest modest reductions in perceived stress and cortisol. Rare liver-injury reports and thyroid interactions make it worth mentioning to your clinician, and many take breaks rather than running it year-round.

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Probiotic

supplement
Dietary supplementGeneral health / gut

Live microorganisms taken for gut health. Evidence is strain- and situation-specific (e.g., around antibiotics); generic daily use has weaker support. Fermented foods are a reasonable alternative worth discussing.

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Fiber (psyllium husk)

supplement
Dietary supplementGeneral health / gut

A soluble fiber with solid evidence for regularity and LDL cholesterol support. Commonly tracked on GLP-class protocols where constipation and low food volume are common. Start low and drink plenty of water.

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Berberine

supplement
Dietary supplementMetabolic support

A plant alkaloid studied for blood sugar and lipids, with modest effects in trials. It meaningfully interacts with many medications (including diabetes drugs), so it belongs in a clinician conversation — especially if you're already on metabolic medication.

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NAC

supplement
Dietary supplementGeneral health / antioxidant

A cysteine source that supports glutathione, the body's main antioxidant. Discussed for respiratory health and antioxidant support. Wellness-use evidence is mixed — worth an honest trial with a defined outcome.

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CoQ10

supplement
Dietary supplementGeneral health / cellular energy

A compound central to mitochondrial energy production, most commonly discussed alongside statin therapy (statins lower CoQ10 levels) and for heart health. Ubiquinol is the better-absorbed form.

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