Thymosin Beta-4
peptideTB4 · parent of TB-500
Recovery-focused research peptide
Research status · Not FDA-approved
Not FDA-approved for human use; a research peptide. TB-500 is a synthetic fragment often marketed under this name. No completed human randomized trials; prohibited in sport (WADA).
Thymosin Beta-4 is a naturally occurring peptide discussed in tissue-repair contexts and closely related to the marketed TB-500 fragment. It is not approved for human use and human data are sparse — clinician guidance is essential.
How it works
Involved in actin regulation, cell migration, and tissue-repair signaling (largely preclinical).
Commonly discussed use cases
- Soft-tissue recovery (discussed)
- Range of motion (discussed)
Supposed / potential benefits
- Repair claims are largely preclinical/anecdotal, not established in humans
Common side effects
- Injection-site reactions
- Headache/lethargy (reported)
- Unknown long-term effects
Warnings & contraindications
- Not FDA-approved; flagged for compounding safety concerns
- Banned in sport (WADA)
- Unregulated sourcing risk
Typical timing considerations
No established regimen; any use should be clinician-directed. Exhaust conventional rehab first.
Administration route
Subcutaneous or intramuscular injection
Storage
Refrigerate after reconstitution; follow instructions.
Questions to ask your clinician
- Should conventional rehab come first?
- What are the risks given limited human evidence?
Commonly tracked in Reta
Tracking fields organize user-entered, clinician-directed routines — Reta never recommends or computes doses.
Sources
Track this in Reta
Beta members get a ready-made tracker for Thymosin Beta-4 — schedule, dose log, injection-site rotation, reminders, and check-ins — for organizing a clinician-directed routine. Personal tracking is available to everyone during the Public Beta.
Reta is a tracking and education tool — not a medical provider. Nothing here is a diagnosis, treatment, prescription, or dosing recommendation. Peptides and medications should only be used under the direction of a licensed clinician. Talk to a qualified clinician before starting, stopping, combining, or changing anything. Many compounds below are not FDA-approved for human use; some are investigational or sold through unregulated channels where purity and dosing are not guaranteed.