NAD+
otherNMN / NR precursors · IV NAD+
Coenzyme / longevity wellness
Research status · Dietary supplement
NAD+ precursors (NMN, NR) are sold as dietary supplements; injectable/IV NAD+ is offered in wellness clinics and is not an FDA-approved treatment for aging or disease. Human evidence is early.
NAD+ is a coenzyme central to cellular energy metabolism. Oral precursors (NMN, NR) are supplements; IV/injectable NAD+ is a clinic-based wellness offering, not an approved therapy. Benefits in humans are still being studied.
How it works
NAD+ is essential to mitochondrial energy production and cellular repair enzymes; supplementation aims to raise NAD+ availability.
Commonly discussed use cases
- Energy (discussed)
- Longevity/wellness (discussed)
- Recovery (discussed)
Supposed / potential benefits
- Early human research; subjective energy claims not firmly established
Common side effects
- Flushing, nausea (especially IV)
- GI upset with oral precursors
- Generally well tolerated at supplement doses
Warnings & contraindications
- Not an FDA-approved treatment for aging or disease
- IV administration carries infusion-related risks and should be clinician-supervised
Typical timing considerations
Oral precursors typically taken daily; IV sessions are clinic-scheduled. Follow product/clinic guidance.
Administration route
Oral (precursors), or IV/subcutaneous (clinic)
Questions to ask your clinician
- Is there a reason to prefer precursors vs IV?
- Any interactions with my medications?
- What would a fair trial period and success measure look like?
Commonly tracked in Reta
Tracking fields organize user-entered, clinician-directed routines — Reta never recommends or computes doses.
Track this in Reta
Beta members get a ready-made tracker for NAD+ — schedule, dose log, injection-site rotation, reminders, and check-ins — for organizing a clinician-directed routine. Personal tracking is available to everyone during the Public Beta.
Reta is a tracking and education tool — not a medical provider. Nothing here is a diagnosis, treatment, prescription, or dosing recommendation. Peptides and medications should only be used under the direction of a licensed clinician. Talk to a qualified clinician before starting, stopping, combining, or changing anything. Many compounds below are not FDA-approved for human use; some are investigational or sold through unregulated channels where purity and dosing are not guaranteed.