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Ipamorelin

peptide

Growth-hormone secretagogue (ghrelin/GHRP receptor agonist)

Research status · Not FDA-approved

Not FDA-approved for human use. Tested in early research; available (where legal) via compounding. Verify current compounding status.

Ipamorelin is a selective growth-hormone secretagogue often discussed alongside CJC-1295. It is not approved; human data are limited.

How it works

Agonist at the ghrelin/growth-hormone-secretagogue receptor, prompting a pulse of the body's own growth hormone with relatively selective action.

Commonly discussed use cases

  • Recovery (discussed)
  • Sleep (discussed)
  • Body composition (discussed)

Supposed / potential benefits

  • Selective GH release with less effect on cortisol/prolactin than older GHRPs (reported)

Common side effects

  • Headache
  • Flushing
  • Increased hunger
  • Injection-site reactions
  • Water retention

Warnings & contraindications

  • Not FDA-approved; long-term safety unknown
  • Unregulated sourcing risk
  • GH-axis stimulation warrants clinician oversight and labs

Typical timing considerations

Community discussions mention pre-sleep/fasted timing; only a clinician should direct this.

Administration route

Subcutaneous injection

Storage

Refrigerate after reconstitution; follow clinician/pharmacy instructions.

Questions to ask your clinician

  • What monitoring do you recommend on the GH axis?
  • Any interactions with my current medications?
  • What outcome would tell us it's worth continuing?

Commonly tracked in Reta

Sleep ratingRecoveryHunger changesInjection site rotationLab dates

Tracking fields organize user-entered, clinician-directed routines — Reta never recommends or computes doses.

Sources

Track this in Reta

Beta members get a ready-made tracker for Ipamorelin — schedule, dose log, injection-site rotation, reminders, and check-ins — for organizing a clinician-directed routine. Personal tracking is available to everyone during the Public Beta.

Reta is a tracking and education tool — not a medical provider. Nothing here is a diagnosis, treatment, prescription, or dosing recommendation. Peptides and medications should only be used under the direction of a licensed clinician. Talk to a qualified clinician before starting, stopping, combining, or changing anything. Many compounds below are not FDA-approved for human use; some are investigational or sold through unregulated channels where purity and dosing are not guaranteed.