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SS-31 (Elamipretide)

peptide

Mitochondrial-targeted peptide

Research status · Investigational

Not FDA-approved. Investigational; studied in clinical trials for certain mitochondrial and cardiovascular conditions. Products sold outside trials are unregulated.

SS-31 (elamipretide) is an investigational mitochondria-targeting peptide studied in specific disease trials. It is not an approved medication, and general wellness evidence is not established.

How it works

Associates with cardiolipin in the inner mitochondrial membrane and is studied for effects on mitochondrial energy efficiency.

Commonly discussed use cases

  • Mitochondrial function (research)
  • Recovery/energy (discussed, unproven)

Supposed / potential benefits

  • Effects studied mainly in disease-specific trials — not established for general use

Common side effects

  • Injection-site reactions
  • Limited human safety data outside trials

Warnings & contraindications

  • Investigational — efficacy/safety for wellness use not established
  • Unregulated sourcing risk

Typical timing considerations

No established wellness regimen; any use should be clinician-directed.

Administration route

Subcutaneous injection

Storage

Refrigerate after reconstitution; follow instructions.

Questions to ask your clinician

  • Is there a trial rather than sourcing this elsewhere?
  • What evidence applies to my goal?

Commonly tracked in Reta

Doses loggedEnergy ratingInjection site rotation

Tracking fields organize user-entered, clinician-directed routines — Reta never recommends or computes doses.

Sources

Track this in Reta

Beta members get a ready-made tracker for SS-31 (Elamipretide) — schedule, dose log, injection-site rotation, reminders, and check-ins — for organizing a clinician-directed routine. Personal tracking is available to everyone during the Public Beta.

Reta is a tracking and education tool — not a medical provider. Nothing here is a diagnosis, treatment, prescription, or dosing recommendation. Peptides and medications should only be used under the direction of a licensed clinician. Talk to a qualified clinician before starting, stopping, combining, or changing anything. Many compounds below are not FDA-approved for human use; some are investigational or sold through unregulated channels where purity and dosing are not guaranteed.